Amira Zarrouk Selected Research

7-ketocholesterol

1/2021	7-Ketocholesterol: Effects on viral infections and hypothetical contribution in COVID-19.
10/2020	Prevention by Dietary Polyphenols (Resveratrol, Quercetin, Apigenin) Against 7-Ketocholesterol-Induced Oxiapoptophagy in Neuronal N2a Cells: Potential Interest for the Treatment of Neurodegenerative and Age-Related Diseases.
1/2020	7-Ketocholesterol- and 7β-Hydroxycholesterol-Induced Peroxisomal Disorders in Glial, Microglial and Neuronal Cells: Potential Role in Neurodegeneration : 7-ketocholesterol and 7β-hydroxycholesterol-Induced Peroxisomal Disorders and Neurodegeneration.
10/2018	Modulation of Kv3.1b potassium channel level and intracellular potassium concentration in 158N murine oligodendrocytes and BV-2 murine microglial cells treated with 7-ketocholesterol, 24S-hydroxycholesterol or tetracosanoic acid (C24:0).
10/2017	Argan Oil-Mediated Attenuation of Organelle Dysfunction, Oxidative Stress and Cell Death Induced by 7-Ketocholesterol in Murine Oligodendrocytes 158N.
10/2017	Comparison of the effects of major fatty acids present in the Mediterranean diet (oleic acid, docosahexaenoic acid) and in hydrogenated oils (elaidic acid) on 7-ketocholesterol-induced oxiapoptophagy in microglial BV-2 cells.
1/2017	Attenuation of 7-ketocholesterol-induced overproduction of reactive oxygen species, apoptosis, and autophagy by dimethyl fumarate on 158N murine oligodendrocytes.
1/2017	7-Ketocholesterol is increased in the plasma of X-ALD patients and induces peroxisomal modifications in microglial cells: Potential roles of 7-ketocholesterol in the pathophysiology of X-ALD.
1/2017	Mitochondrial dysfunctions in 7-ketocholesterol-treated 158N oligodendrocytes without or with α-tocopherol: Impacts on the cellular profil of tricarboxylic cycle-associated organic acids, long chain saturated and unsaturated fatty acids, oxysterols, cholesterol and cholesterol precursors.
11/2016	Protective Effects of α-Tocopherol, γ-Tocopherol and Oleic Acid, Three Compounds of Olive Oils, and No Effect of Trolox, on 7-Ketocholesterol-Induced Mitochondrial and Peroxisomal Dysfunction in Microglial BV-2 Cells.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Amira Zarrouk Research Topics

Disease

15	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 07/2013
11	Mitochondrial Diseases (Mitochondrial Disease) 10/2020 - 01/2012
8	Alzheimer Disease (Alzheimer's Disease) 01/2021 - 01/2012
3	Inflammation (Inflammations) 11/2021 - 11/2014
3	Multiple Sclerosis 01/2021 - 01/2017
3	Dementia (Dementias) 01/2020 - 01/2015
3	Rupture 01/2020 - 01/2017
3	Coronary Artery Disease (Coronary Atherosclerosis) 03/2018 - 01/2017
2	COVID-19 05/2022 - 01/2021
2	Cognitive Dysfunction 06/2021 - 01/2015
2	Frailty 01/2020 - 01/2020
2	Peroxisomal Disorders (Peroxisomal Disorder) 01/2020 - 01/2017
2	Adrenoleukodystrophy (Adrenoleukodystrophy, X-Linked) 01/2020 - 01/2017
2	Demyelinating Diseases (Demyelinating Disease) 01/2019 - 01/2017
2	Atherosclerosis 08/2017 - 01/2017
1	Infections 05/2022
1	Sarcopenia 11/2021
1	Body Weight (Weight, Body) 06/2021
1	Amnesia (Dissociative Amnesia) 06/2021
1	Neoplasms (Cancer) 01/2021
1	Neuroblastoma 01/2021
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2021
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2021
1	Macular Degeneration (Age-Related Maculopathy) 01/2021
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2021
1	Necrosis 01/2021
1	Relapsing-Remitting Multiple Sclerosis 11/2019
1	Prodromal Symptoms 01/2018
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2017
1	Glioma (Gliomas) 07/2015
1	Vascular Dementia (Subcortical Arteriosclerotic Encephalopathy) 01/2015

Drug/Important Bio-Agent (IBA)

13	7-ketocholesterolIBA 01/2021 - 07/2013
13	CholesterolIBA 10/2020 - 07/2013
12	OxysterolsIBA 11/2021 - 11/2014
10	LipidsIBA 01/2021 - 01/2012
9	Fatty Acids (Saturated Fatty Acids)IBA 11/2019 - 01/2015
6	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2015
4	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 01/2017
3	Proteins (Proteins, Gene)FDA Link 10/2020 - 01/2015
3	PlasmalogensIBA 01/2020 - 01/2017
3	Caspase 3 (Caspase-3)IBA 11/2019 - 10/2017
2	OilsIBA 11/2021 - 01/2021
2	milk-thistle extractIBA 01/2021 - 07/2018
2	Cardiolipins (Cardiolipin)IBA 11/2019 - 10/2018
2	AcidsIBA 11/2019 - 01/2017
2	OxidesIBA 10/2018 - 11/2014
2	lignoceric acid (tetracosanoic acid)IBA 10/2018 - 01/2015
2	Tocopherols (Tocopherol)IBA 01/2017 - 01/2017
1	Pharmaceutical PreparationsIBA 01/2022
1	Cholinergic Agents (Cholinergics)IBA 06/2021
1	Advanced Glycation End ProductsIBA 06/2021
1	Scopolamine (Hyoscine)FDA Link 06/2021
1	CoagulantsIBA 01/2021
1	Antiviral Agents (Antivirals)IBA 01/2021
1	ApigeninIBA 10/2020
1	PolyphenolsIBA 10/2020
1	QuercetinIBA 10/2020
1	AMP-Activated Protein KinasesIBA 10/2020
1	Biological ProductsIBA 10/2020
1	ResveratrolIBA 10/2020
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 10/2020
1	Sirtuin 1IBA 10/2020
1	Arachidonic Acid (Vitamin F)IBA 01/2020
1	Interleukin-6 (Interleukin 6)IBA 01/2020
1	Interleukin-8 (Interleukin 8)IBA 01/2020
1	CytokinesIBA 01/2020
1	citraconic acid (mesaconic acid)IBA 11/2019
1	Succinate Dehydrogenase (Fumarate Reductase)IBA 11/2019
1	Dimethyl FumarateIBA 11/2019
1	Plant ExtractsIBA 04/2019
1	Biotin (Vitamin H)FDA Link 01/2019
1	egg-oilIBA 10/2018
1	24-hydroxycholesterolIBA 10/2018
1	EnzymesIBA 10/2018
1	Messenger RNA (mRNA)IBA 10/2018
1	Potassium Channels (Potassium Channel)IBA 10/2018
1	Ion Channels (Ion Channel)IBA 10/2018
1	Adenosine Triphosphate (ATP)IBA 10/2018
1	Trans Fatty AcidsIBA 03/2018
1	Phospholipids (Phosphatides)FDA LinkGeneric 01/2018
1	argan oilIBA 10/2017
1	Docosahexaenoic AcidsIBA 01/2017
1	Phytanic AcidIBA 01/2017
1	Malondialdehyde (Propanedial)IBA 01/2017
1	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 01/2017
1	C-Reactive ProteinIBA 01/2017
1	ProfilIBA 01/2017
1	CalciumIBA 07/2015
1	27-hydroxycholesterolIBA 07/2015
1	Gentian Violet (Violet, Crystal)FDA Link 07/2015
1	Phytosterols (Plant Sterols)IBA 07/2015
1	TubulinIBA 01/2015
1	DNA (Deoxyribonucleic Acid)IBA 01/2015
1	hexacosanoic acidIBA 01/2015
1	Trypan Blue FDA Link 01/2012

Therapy/Procedure

3	Mediterranean Diet 11/2021 - 08/2017
2	Therapeutics 05/2022 - 01/2021
1	Oral Administration 06/2021
1	Home Nursing (Nursing, Home) 01/2020
1	Polypharmacy 01/2020